The Journal of Health, Population and Nutrition
Vol. 35, No. 1, 2016, pp. 1-4
Bioline Code: hn16003
Full paper language: English
Document type: Research Article
Document available free of charge
The Journal of Health, Population and Nutrition, Vol. 35, No. 1, 2016, pp. 1-4
© Copyright 2016 - The Journal of Health, Population and Nutrition
Mean platelet volume in children with hepatitis A|
Akın, Fatih; Sert, Ahmet & Arslan, Şükrü
Background: Mean platelet volume (MPV), which is commonly used as a measure of platelet size, indicates the rate
of platelet production and platelet activation. We aimed to evaluate the mean platelet volume in children with
Methods: In this retrospective case-controlled study, the study population consisted of 62 children with hepatitis A
and 62 healthy control subjects.
Results: MPV values, aspartate transaminase (AST), and alanine transaminase (ALT) levels on admission were
significantly increased in patients with hepatitis A when compared to controls whereas white blood cell (WBC)
counts were significantly lower. Two weeks after admission, the MPV values showed a significant decrease from 9.
47 ± 1.62 to 8.84 ± 1.48 fL in patients with hepatitis A, but these values were still significantly higher than the
controls. There was a significant difference in terms of MPV, WBC, AST, and ALT values between the controls and
the patient group 2 weeks after admission.
Conclusions: This study is the first to evaluate the MPV levels in children with hepatitis A. MPV values were found
to be increased in children hospitalized with hepatitis A.
Viral infection; Child; Inflammation; Cytokines
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