About Bioline  All Journals  Testimonials  Membership  News

African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 9, No. 4, 2009, pp. 275-278
Bioline Code: hs09065
Full paper language: English
Document type: Research Article
Document available free of charge

African Health Sciences, Vol. 9, No. 4, 2009, pp. 275-278

 en Synthesis, characterization and biological activities of substituted cinnoline culphonamides
Vikas, S & Darbhamulla, S


Background: The Cinnoline moiety and Sulphonamide moiety both have good antimicrobial properties.
Methods: In the present study both the moieties were condensed to synthesize substituted cinnoline sulphonamide derivatives using intramolecular cyclization followed by diazotization in order to get synergistic activity.
Results: These derivatives particularly halogen substituted cinnoline derivatives showed potent antimicrobial activity.
Conclusion: Further investigations are required to find out possible mechanism of action.

Cinnoline, Antibacterial, Antifungal

© Copyright 2009 - Makerere Medical School, Uganda

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2023, Site last up-dated on 01-Sep-2022.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Google Cloud Platform, GCP, Brazil