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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 10, No. 3, 2010, pp. 218-225
Bioline Code: hs10044
Full paper language: English
Document type: Research Article
Document available free of charge

African Health Sciences, Vol. 10, No. 3, 2010, pp. 218-225

 en Epilepsy in rural Ugandan children: Seizure pattern, age of onset and associated findings
Duggan, M.B.


Introduction: Much information on childhood epilepsy in sub Saharan Africa is hospital based. A survey was considered necessary before integrating epilepsy management into a Ugandan community programme.
Method: Using an 'outreach′ method, children with recurrent seizures were offered assessment at 19 sites in Rukungiri District. A brief history and neurological and developmental assessment was carried out on each child. A clinical diagnosis of epilepsy, including seizure type, was given to 440 of 618 children < 18 years with 178 exclusions.
Results: The age-specific prevalence of epilepsy in children < 15 years was 2.04% (95% CI 1.94 % to 2.24 %) based on 395 cases in an < 15 years population of 193,126. Percentage distribution by seizure type was:-generalised tonic-clonic (53%), complex partial seizures CPS (27%), simple partial and miscellaneous seizures (6% each), with some diagnostic overlap between seizure types. Cerebral palsy, evident or evolving, was most strongly associated with CPS. A positive perinatal or infantile history was noted in 12 and 6% respectively, and 50.2% of seizures began in infancy.
Conclusions: The prevalence of epilepsy is similar in Gambian children. The high contribution from early-onset CPS, resembles Kenyan reports of malaria- associated CPS, suggesting a causal association with malaria.

seizure type, associated findings, age-specific prevalence, possible malaria association

© Copyright 2010 African Health Sciences.

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