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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 11, No. 2, 2011, pp. 285 - 287
Bioline Code: hs11044
Full paper language: English
Document type: Case Report
Document available free of charge

African Health Sciences, Vol. 11, No. 2, 2011, pp. 285 - 287

 en Squamous Cell Carcinoma arising in a mature cystic ovarian Teratoma with bladder invasion: a Case Report
Badmos, K.B.; Ibrahim, O.K.; Aboyeji, A.P. & Omotayo, J.A.

Abstract

Background: Malignant transformation in a mature cystic ovarian teratoma is rare. Except in cases with high index of suspicion or overt metastasis, oophorectomy is the mainstay of treatment for ovarian teratoma.
Method: A 46-year-old perimenopausal woman who had salpingo-oophorectomy following a clinical diagnosis of benign ovarian tumour that was subsequently reported histologically as mature cystic ovarian teratoma with malignant transformation is presented.
Results: She was referred to our facility based on the histopathology report and haematuria two weeks after surgery. Cystoscopic biopsy done was reported as metastatic squamous cell carcinoma most probably from the ovary. Patient was thereafter referred for radiotherapy but was lost to follow-up after the first course.
Conclusion: Adequate evaluation prior to surgery in suspected ovarian teratoma with malignant transformation is critical to determine extent of surgery and adjuvant therapy. Prognosis in advanced disease condition such as the case presented is generally poor although radical pelvic surgery with resection of the adjacent involved bladder before radiotherapy would probably have improved her prognosis.

Keywords
ovarian teratoma, malignant, perimenopausal, radiotherapy

 
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