African Health Sciences
Makerere University Medical School
Vol. 12, No. 1, 2012, pp. 69-73
Bioline Code: hs12012
Full paper language: English
Document type: Research Article
Document available free of charge
African Health Sciences, Vol. 12, No. 1, 2012, pp. 69-73
© Copyright © 2012 - African Health Sciences
Analysis of Gleason grade and scores in 90 Nigerian Africans with prostate cancer during the period 1994 to 2004|
Ugare, UG; Bassey, IE; Jibrin, PG & Ekanem, IA
To determine the relative frequency of prostate cancer among surgical specimens, and among prostate specimens received at the pathology department ,University Hospital Calabar.
Histology records were reviewed for the following: total number of histology specimens received; total number of prostate specimens; total number of prostate cancer; and the total number of cancers in males during the study period. Histology sections 4-5microns thick were cut from paraffin blocks and stained by Haematoxylin and Eosin (H&E). Histopathologic specimens were classified using the grading system of tumour differentiation described by Gleason and associates.
One hundred and twenty three cancers of the prostate were received, constituting 2% of the total surgical specimens and 31% of prostate specimens. Thirty three cases (27%) could not be analyzed; therefore the study is based on 90 prostate cancer specimens. Eighty nine (99%) cases were epithelial tumours (adenocarcinoma.) There was a single mesenchymal tumour (rhabdomyosarcoma) (1%). The commonest grade in this study was the high grade (Gleason grade IV).
We observed that prostate cancer is a common among males (all sites) diagnosed at the University Hospital Calabar, with a peak incidence between the ages of 61 - 70 years (seventh decade).
prostate, cancer, analysis, histologic, pattern, role, grade