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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 12, No. 3, 2012, pp. 331-333
Bioline Code: hs12053
Full paper language: English
Document type: Research Article
Document available free of charge

African Health Sciences, Vol. 12, No. 3, 2012, pp. 331-333

 en Profound reduction of CD4+ lymphocytes without HIV infection: two cases from the horn of Africa
Ollé-Goig, JE; Ramírez, J; Cervera, C & Miró, JM

Abstract

Idiopathic CD4+ lymphocytopenia is a disorder associated with low CD4+ T cell count and opportunistic infections resembling AIDS. Most cases are described in developed countries. We report two HIV-negative patients with idiopathic CD4+ lymphocytopenia and AIDS-defining events diagnosed in Djibouti. The first patient developed lesions of Kaposi’s sarcoma and the second one presented with pulmonary tuberculosis. Both patients died with severe immunodepression. In poor resource-areas where HIV testing may not be available it is important to bear in mind that severe immunodepression and a clinical presentation compatible with AIDS do not necessary carry the diagnosis of AIDS.

Keywords
Human immunodeficiency virus, Acquired immunodeficiency syndrome, Lymphopenia, Kaposi’s sarcoma, tuberculosis, Djibouti

 
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