African Health Sciences
Makerere University Medical School
Vol. 12, No. 4, 2012, pp. 557-562
Bioline Code: hs12094
Full paper language: English
Document type: Research Article
Document available free of charge
African Health Sciences, Vol. 12, No. 4, 2012, pp. 557-562
© Copyright 2012 - African Health Sciences
Clinical “case series”: a concept analysis|
Abu-Zidan, FM; Abbas, AK & Hefny, AF
Objectives: To analyze the concept of “case series” in the medical literature compared with case reports.
Methods: A PubMed search for articles published during 2009 which had “case series” in their title was performed. A total
number of 621 articles were retrieved. 586 papers were included in the analysis and 35 were excluded (18 were commentary
letters, 5 were not in English, and twelve could not be retrieved by our Library). The number of patients and category of
these articles were analyzed.
Results: The median (range) of the number of cases of articles having “case series” in their title was 7 (1-6432) cases. 186/
586 articles had less than 5 cases (31.7%, 95% CI (28.3-35.1%)). The median (range) of the number of cases of articles
having “case report” as their publication type was 4 (1-178) cases. Out of the 219 articles categorized as case reports 114
(52.1%, 95% CI (45.6-58.6%)) had less than five cases.
Conclusions: The concept of “case series” is not well defined in the literature and does not reflect a specific research design.
We suggest that a case series should have more than four patients while four paitents or less should be reported individually
as case reports.
Case report, case series, concept analysis, research design