African Health Sciences
Makerere University Medical School
Vol. 13, No. 1, 2013, pp. 94-99
Bioline Code: hs13015
Full paper language: English
Document type: Case Report
Document available free of charge
African Health Sciences, Vol. 13, No. 1, 2013, pp. 94-99
© Copyright 2012 - African Health Sciences
Henoch Schonlein Purpura in children: clinical analysis of 120 cases|
Chen, O; Zhu, XB; Ren, P; Wang, YB; Sun, RP & Wei, DE
Background: Henoch Schonlein Purpura (HSP) is a systemic vasculitic disease which is common in children. It is very
important to understand the clinical features of this disease for doctors and nurses.
Objective: To study the clinical characteristics of HSP in children.
Methods:Collect the clinical data of the HSP children, and analyze the clinical characteristics of these HSP patients.
Results:The ratio of M:F was 1.9:1. The mean age was 6.6 ± 1.6 years. The typical onset seasons were spring, winter and
autumn. Infection and food allergy were the main etiological factors. The first symptom was skin purpura and these
purpura mainly concentrated the lower extremities and buttocks. The dominant digestive clinical features were abdominal
pains and vomiting. The knee joint and ankle joint were most frequently affected. The typical kidney symptoms were
microscopic hematuria and albuminuria. An increased ESR was reported in 68 patients (56.7%). Serum C3 decreased in 13
cases (10.8%). ASO titer was higher in 57 children (47.5%).
Conclusion:There were gender, season and area differences for the HSP patients. The etiological factors were diverse. HSP
patients could have various clinical symptoms and rare complications.
Henoch Schonlein Purpura, Children