About Bioline  All Journals  Testimonials  Membership  News

African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 13, No. 3, 2013, pp. 571-578
Bioline Code: hs13088
Full paper language: English
Document type: Research Article
Document available free of charge

African Health Sciences, Vol. 13, No. 3, 2013, pp. 571-578

 en Effect of interval training programme on pulse pressure in the management of hypertension: a randomized controlled trial
Sikiru, L & Okoye, GC


Background: Pulse pressure (PP), might be a stronger determinants of cardiovascular risk.
Objective: To investigate the effect of interval training program on PP in subjects with hypertension.
Methods: Two hundred and forty five male patients with mild to moderate (Systolic Blood Pressure [SBP] between 140-179 & Diastolic Blood Pressure [DBP] between 90-109 mmHg) essential hypertension were age-matched and grouped into exercise and control groups. The exercise (work: rest ratio of 1:1) groups involved in an 8-weeks interval training programs of between 45-60 minutes, at intensities of 60-79% of HR max (maximum heart rate), while the control group remained sedentary during this period. SBP, DBP, VO2max and PP were assessed.
Results: Findings of the study revealed significant correlation between PP and blood pressure;correlation of PP with SBP was much stronger (95% variance). Also, there was significant effect of the exercise training program on SBP, DBP and PP. Changes in VO2max also negatively correlated with changes in PP (r= -.285) at p<0.05.
Conclusion: Moderate intensity interval training programs is effective in the non-pharmacological management of hypertension and may prevent cardiovascular event through the down regulation of PP in hypertension.

Hypertension, Interval exercise, pulse pressure, cardiovascular risk factor, Blood pressure.

© African Health Sciences

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2024, Site last up-dated on 01-Sep-2022.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Google Cloud Platform, GCP, Brazil