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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 13, No. 4, 2013, pp. 999-1006
Bioline Code: hs13140
Full paper language: English
Document type: Research Article
Document available free of charge

African Health Sciences, Vol. 13, No. 4, 2013, pp. 999-1006

 en Effects of intravenous diclofenac on postoperative sore throat in patients undergoing laparoscopic surgery at Aga Khan University Hospital, Nairobi: A prospective, randomized, double blind controlled trial
Thang’a, P.; Kamya, D. & Mung’ayi, V.


Background: postoperative sore throat is the commonest complication after endotracheal intubation. The efficacy of intravenous non-steroidal anti-inflammatory drugs in alleviating postoperative sore throat has not been investigated.
Objective: To evaluate the effect of intravenous diclofenac sodium on the occurrence and severity of postoperative sore throat.
Methods: 42 in-patients scheduled for laparoscopic surgery were randomized into two equal groups to receive either a single dose of 75mg intravenous diclofenac sodium in addition to standard treatment taken at our hospital for the prevention of postoperative sore throat or to receive standard treatment only. All patients were interviewed postoperatively at 2, 6 and 18 hours. Data of the baseline characteristics, the incidence and severity of sore throat were collected. If sore throat was present,a Visual Analogue Score was used to assess its severity.
Results: the baseline characteristics of the participants were similar. The majority of the patients undergoing laparoscopic surgery were women. There was no statistically significant difference in the occurrence or severity of postoperative sore throat between the diclofenac and standard treatment groups at 2, 6 and 18 hours postoperatively.
Conclusion: Intravenous diclofenac sodium does not reduce the occurrence or severity of postoperative sore throat.

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