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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 2, No. 14, 2014, pp. 364-371
Bioline Code: hs14054
Full paper language: English
Document type: Research Article
Document available free of charge

African Health Sciences, Vol. 2, No. 14, 2014, pp. 364-371

 en Bacillus check for this species in other resources Spp. isolated from the conjunctiva and their potential antimicrobial activity against other eye pathogens
Kıvanç, Sertaç Argun; Takım, Murat; Kıvanç, Merih & Güllülü, Gülay

Abstract

Background: In this study, we attempted to screen and investigate antibacterial activity of Bacillus check for this species in other resources species, which were isolated from conjunctiva, against other eyes pathogens.
Methods: To examine predominant isolates of Bacillus subtilis check for this species in other resources , B. pumilus check for this species in other resources , B. cereus check for this species in other resources and B. mojevensis check for this species in other resources , isolated from conjunctiva for their antimicrobial activity against indicator microorganisms as Micrococcus luteus check for this species in other resources , Staphyloccocus aureus check for this species in other resources , S. epidermidis check for this species in other resources , S. hominis check for this species in other resources , S. lugdunensis check for this species in other resources , S. warneri check for this species in other resources , S. haemolyticus check for this species in other resources , B. cereus, Listeria monocytogenes check for this species in other resources , and Proteus mirabilis check for this species in other resources . Growth inhibitions of indicator microorganisms were tested using agar diffusion tests by cells and supernatants of five B. mojevensis, one B. subtilis, four B. cereus and five B. pumilus strains which were isolated from conjunctiva.
Results:The Bacillus isolates showed variable ability of inhibition against the tested microorganisms. Two strains of B. pumillus, 1 strain of B. subtilis, 5 strains of B. mojevensis, 1 strain of B. cereus were efficacious against the tested microorganisms. Most resistant microorganism to these bacteria was Proteus mirabilis. Two of Gram positive bacteria, S. lugdenensis (K15-9) and S. aureus (SDA48), were also found as resistant.
Conclusions: In this study, Bacillus spp isolated from conjunctiva showed antimicrobial activity against Gram-positive bacteria. Human eye-derived microorganisms and their antimicrobial effects might be a useful source of natural products for the future.

Keywords
Bacillus spp; antibacterial activity; eyes pathogens; conjunctiva

 
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