Background: Multi-resistant microorganisms such as
Escherichia coli
,
Staphylococcus aureus
,
Pseudomonas aeruginosa
,
Candida tropicalis
e
Candida krusei
are the main causes of microbial infections.
Padina sanctae-crucis
is a seaweed often used to check the contamination of ecosystems by materials such as heavy metals, but studies of the antimicrobial activity of the same seaweed were not found.
Methods: The tests for the minimum inhibitory concentration and modulation of microbial resistance, with the use of ethanolic and methanolic extracts of
Padina Sanctae-cruces combined with drugs of the class of aminoglycosides and antifungal were used to evaluate the activity against the cited microorganisms.
Results: Was observed a modulation of antibiotic activity between the natural products and the
E. col and
S. aureus strains, indicating a synergism and antagonism respectively.
Conclusions: The results showed a moderate modulatory effect against some microorganisms studied.
