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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 14, No. 2, 2014, pp. 372-376
Bioline Code: hs14055
Full paper language: English
Document type: Research Article
Document available free of charge

African Health Sciences, Vol. 14, No. 2, 2014, pp. 372-376

 en Evaluation of antibacterial, antifungal and modulatory activity of methanol and ethanol extracts of Padina sanctae-crucis check for this species in other resources
Nogueira, Lavouisier F.B.; Morais, Edson C.; Brito, Maria A.D.; Santos, Beatriz S.; Vale, Doanny L.; Lucena, Bruno F.F.; Figueredo, Fernando G.; Guedes, Glaucia M.M.; Tintino, Saulo R.; Souza, Celestina E. S.; Nogueira, Raquel B.S.S.; Matias, Edinardo F.F.; Morais-Braga, Maria F.B.; Cunha, Emídio V.L.; Lima, Micheline A. & Coutinho, Henrique D.M.

Abstract

Background: Multi-resistant microorganisms such as Escherichia coli check for this species in other resources , Staphylococcus aureus check for this species in other resources , Pseudomonas aeruginosa check for this species in other resources , Candida tropicalis check for this species in other resources e Candida krusei check for this species in other resources are the main causes of microbial infections. Padina sanctae-crucis check for this species in other resources is a seaweed often used to check the contamination of ecosystems by materials such as heavy metals, but studies of the antimicrobial activity of the same seaweed were not found.
Methods: The tests for the minimum inhibitory concentration and modulation of microbial resistance, with the use of ethanolic and methanolic extracts of Padina Sanctae-cruces combined with drugs of the class of aminoglycosides and antifungal were used to evaluate the activity against the cited microorganisms.
Results: Was observed a modulation of antibiotic activity between the natural products and the E. col and S. aureus strains, indicating a synergism and antagonism respectively.
Conclusions: The results showed a moderate modulatory effect against some microorganisms studied.

Keywords
multi-resistant microorganisms; modulation; Padina Sanctae-crucis; antimicrobial activity

 
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