About Bioline  All Journals  Testimonials  Membership  News

African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 14, No. 3, 2014, pp. 753-756
Bioline Code: hs14111
Full paper language: English
Document type: Research Article
Document available free of charge

African Health Sciences, Vol. 14, No. 3, 2014, pp. 753-756

 en Antibacterial properties studies of trunk barks of terminalia ivorensis check for this species in other resources (Combretaceae), a commercial and medicinal specie, on some methicillin-resistant Staphylococci spp strains.
Coulibaly, K.; Zirihi, G. N.; Guessennd-Kouadio, N.; Oussou, K. R. & Dosso, M.


Background: Methicillin-resistant Staphylococcus aureus check for this species in other resources , Staphylococcus epidermidis check for this species in other resources and coagulase-negative Staphylococcus infections are a worldwide concern. Terminalia ivorensis check for this species in other resources , of Combretaceae family plant, is widely used traditional medicinal in Côte d’Ivoire to treat dermal diseases (affection in which Staphylococci are implied) including local inflammation and also to treat voice-loss.
Objectives: This study focused to investigate the effect in vitro of the extracts of trunk barks of Terminalia ivorensis on some methicillin/oxacillin-resistant strains of Staphylococcus aureus, S. epidermidis, coagulase-negative S. and reference strain of S. aureus ATCC 25923.
Methods: Antibacterial activity of aqueous, 70% ethanolic 70% and aqueous residue extracts was assessed using agar disc-diffusion method and liquid medium microdilution method in 96 multi-well micro-titer plates. This method led us to determine minimum inhibition concentration (M.I.C.) and minimum bactericidal concentration (M.B.C.). The presence of chemical groups major was detected qualitatively.
Results: Aqueous and 70% ethanolic 70% extracts showed significant activity against all the bacteria except aqueous residue when compared with the standard antibiotic oxacillin (5μg/ml). M.I.C. for aqueous and 70% ethanolic 70% extracts ranged from 0,83-16,67 mg/ml and 0,156-13,33 mg/ml respectively. Viable cell determination revealed the bactericidal nature of the two barks extracts. The 70% ethanolic 70% extract exhibited the highest activity according to the M.B.C. values. The phytochemical analysis indicates the presence of tannins, saponins, flavonoids, terpen/sterols, coumarins, polyphenols and traces of alkaloid.
Conclusion: The in-vitro antibacterial efficacy shown by the barks of this plant and his lushness in chimical compounds, would justify use of this one in the traditional treatment of some diseases of microbial origin. These compounds could be suggested to provide alternative solution to the development of new therapeutic agents.

Terminalia ivorensis; Dermal diseases; Methicillin-resistant; Côte d’Ivoire

© Copyright 2014 - African Health Sciences

Home Faq Resources Email Bioline
© Bioline International, 1989 - 2024, Site last up-dated on 01-Sep-2022.
Site created and maintained by the Reference Center on Environmental Information, CRIA, Brazil
System hosted by the Google Cloud Platform, GCP, Brazil