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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 14, No. 4, 2014, pp. 1074-1077
Bioline Code: hs14159
Full paper language: English
Document type: Case Report
Document available free of charge

African Health Sciences, Vol. 14, No. 4, 2014, pp. 1074-1077

 en Lassa fever – full recovery without ribavarin treatment: a case report
Ajayi, Nnennaya A.; Ukwaja, Kingsley N.; Ifebunandu, Ngozi A.; Nnabu, Richard; Onwe, Francis I. & Asogun, Danny A.


Background: Lassa fever is a rodent-borne zoonosis that clinically manifests as an acute hemorrhagic fever. It is treated using ribavarin. Surviving Lassa fever without receiving the antiviral drug ribavarin is rare. Only few cases have been documented to date.
Case Presentation: We report a case of a 59-year old female with fever who was initially thought to have acute pyelonephritis and sepsis syndrome with background malaria. Further changes in her clinical state and laboratory tests led to a suspicion of Lassa fever. However at the time her laboratory confirmatory test for Lassa fever returned, her clinical state had improved and she made full recovery without receiving ribavarin. Her close contacts showed no evidence of Lassa virus infection.
Conclusion: This report adds to the literature on the natural history of Lassa fever; and that individuals may survive Lassa fever with conservative management of symptoms of the disease and its complications.

Lassa fever; viral hemorrhagic fever; survival; ribavarin

© African Health Sciences

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