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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 15, No. 1, 2015, pp. 299-301
Bioline Code: hs15042
Full paper language: English
Document type: Case Report
Document available free of charge

African Health Sciences, Vol. 15, No. 1, 2015, pp. 299-301

 en Hypogammaglobulinemia in sub-Saharan Africa: a case report and review of the literature
Hsu, Jennifer; Opoka, Robert & Lund, Troy C.


Abstract: Patients with hypogammaglobulinemia are susceptible to recurrent bacterial, viral, fungal, and parasitic infections. The most common clinical manifestation includes recurrent severe infections caused by encapsulated bacteria, in which antibody opsonization is the primary defense mechanism. To our knowledge, this is the first case report of hypogammaglobulinemia in a Ugandan child in Sub-Saharan Africa. The case emphasizes the importance of including hypogammaglobulinemia in the differential diagnosis for children presenting with a history of recurrent infections.
Aim: To raise the index of clinical suspicion of hypogammaglobulinemia in an African child and allow for prompt recognition and management of hypogammaglobulinemia.

hypogammaglobulinemia; recurrent infections; Uganda

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