Burden and pattern of micro vascular complications in type 2 diabetes in a tertiary health institution in Nigeria.|
Olamoyegun, Michael; Ibraheem, Waheed; Iwuala, Sandra; Audu, Morenike & Kolawole, Babatope
Introduction: Diabetes mellitus (DM) afflicts at least 5 million people in Nigeria, with more than 80% having type 2 diabetes
mellitus (T2DM). Microvascular complications increase both morbidity and mortality inpatients with T2DM. The aims
of this study were to report the burden of various microvascular complications in T2DM and to identify various factors
associated with these complications in patients with T2DM attending the diabetes outpatients’ clinic.
Methods: Ninety (90) patients with T2DM who have attended diabetes clinic for at least 3 months were recruited for this
study. Detailed history, physical examination and biochemical analysis was done in each of the patients. All patients underwent
a detailed standard evaluation to detect diabetic retinopathy (fundoscopy), neuropathy (10g monofilament and/
or diabetes neuropathy scores), and nephropathy (microalbuminuria, macroalbuminuria, serum creatinine and estimated
glomerular filtration rate).
Results: There was high prevalence of microvascular complications among patients with T2DM. Almost half of patients
with T2DM had some form of microvascular complications; diabetic neuropathy being the commonest (69.6%),followed by
nephropathy (54.5%) and retinopathy (48.9%). The factors associated with developing these complications were increasing
age, duration of diabetes, hypertension and dyslipidaemia for nephropathy and neuropathy.
Conclusion: There is a high burden of microvascular complications in patients with type 2 diabetes. Age, male gender,
hypertension, glycaemic control, BMI and duration of diabetes, and glycaemic control were factors associated with microvasular
Type 2 diabetes; microvascular complications; prevalence; risk factors; Nigeria