African Health Sciences
Makerere University Medical School
Vol. 15, No. 4, 2015, pp. 1182-1188
Bioline Code: hs15163
Full paper language: English
Document type: Research Article
Document available free of charge
African Health Sciences, Vol. 15, No. 4, 2015, pp. 1182-1188
© Copyright 2015 - African Health Sciences
Proportion of patients in the Uganda rheumatic heart disease registry with advanced disease requiring urgent surgical interventions|
Zhang, WanZhu; Okello, Emmy; Nyakoojo, Wilson; Lwabi, Peter & Mondo, Charles K.
Introduction: Since the establishment of the Uganda Rheumatic Heart Registry, over 900 patients have been enrolled. We
sought to stratify the patients in the registry according to disease severity and optimal management strategy.
Methods: We reviewed data of 618 patients who had enrolled in the Registry between March 2010 and February 2013. The
67 patients who had died were excluded leaving 551 patients who were recruited. The optimum management strategy was
determined according to the 2012 European Society of Cardiology guidelines on the management of valvular heart disease.
Results: Out of the 551 patient’s records evaluated, 398 (72.3%) required invasive intervention, with 332(60.3%) patients
requiring surgery and 66 (12.0%) requiring percutaneous mitral commissurotomy (PMC). This leaves only 27.7% of patients
who required only medical management. Currently, majority of the patients (498, 90.4%) in the registry are on medical treatment.
Of the 60.3% requiring surgical intervention, only 8.0% (44 patients) underwent valvular surgery and 5(1.0%) patients
of the 66 (12.0%) underwent PMC successfully.
Conclusion: There is a high proportion of patients with severe disease that require surgical treatment yet they cannot access
this therapy due to absence of local expertise.
Rheumatic Heart Disease; surgical intervention; percutaneuos intervention