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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 17, No. 3, 2017, pp. 738-745
Bioline Code: hs17092
Full paper language: English
Document type: Study
Document available free of charge

African Health Sciences, Vol. 17, No. 3, 2017, pp. 738-745

 en The relationship between patient-related factors and medication adherence among Nigerian patients taking highly active anti-retroviral therapy.
Nduaguba, Sabina O; Soremekun, Rebecca O; Olugbake, Olubusola A & Barner, Jamie C


Background: Through several initiatives, there are increasingly more people who have access to anti-retroviral therapy. Adherence to therapy is, however,necessary for successful management of disease.
Objectives: The objectives of this study were to describe adherence rates and determine what patient-related factors are related to adherence to anti-retroviral therapy among adult patients in an HIV clinic located in Lagos, Nigeria.
Methods: Adherence was measured using the two-week self-recall method. Barriers, satisfaction with therapy, and socio-demographic and clinical variables served as independent variables. Data were collected via self-administered surveys.
Results: . Most of the patients (79.5%) reported 100% adherence. The significant (p<0.05) barriers to adherence were forgetfulness, running out of medication, alcohol use, and medication side effects. For every unit increase in the number of barriers, patients were 60.8% less likely to be 100% adherent (p <0.05, odds ratio, OR = 0.392,95% CI = 0.295-0.523).
Conclusion: Interventions should target helping patients cope with forgetfulness, specifically employing strategies to overcome busyness in schedules, being away from home, and tiredness.

Medication adherence; patients; anti-retroviral therapy

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