African Health Sciences
Makerere University Medical School
Vol. 18, No. 1, 2018, pp. 102-110
Bioline Code: hs18014
Full paper language: English
Document type: Study
Document available free of charge
African Health Sciences, Vol. 18, No. 1, 2018, pp. 102-110
© Copyright 2018 - African Health Sciences
Clinical implication of smoking among patients with schizophrenia at a Tertiary Institution in South East Nigeria|
Aguocha, Chinyere; Uwakwe, Richard; Olose, Emmanuel; Amadi, Kennedy; Onyeama, Gabriel & Duru, Chukwuma
Background: The chronic and debilitating nature of schizophrenia creates a disease with marked clinical and economic consequences.
Smoking in schizophrenia appears to be associated with increased psychopathology and disability.
Objective: The aim of this study was to determine if cigarette smoking in schizophrenia is associated with increased disability
Materials and methods: This was a cross-sectional descriptive study in which 367 out-patients with International Classification
of Diseases (ICD) 10 diagnosis of schizophrenia were recruited. Socio-demographic questionnaire, Present State Examination
(PSE) 10, Positive And Negative Syndrome Scale (PANSS) and World Health Organization Disability Assessment Schedule
(WHODAS) were administered. Data was analyzed using a software package SPSS version 15.
Results: There was no significant difference in the mean PANSS scores of smokers and non-smokers. Current smoking was
associated with increased disability (F=5.39, p=0.02). Total PANSS score significantly predicted disability F(3,71=5.60, p=0.002,
R2=0.19). There was no significant association between positive or negative symptoms and being a smoker or non-smoker.
Conclusion: The results of this study revealed that smoking in Nigerian schizophrenia patients is associated with significant
disability. Measures should be put in place to discourage cigarette smoking among Nigerian patients with schizophrenia.
Schizophrenia; smoking; psychopathology; disability; Nigeria.