African Health Sciences
Makerere University Medical School
Vol. 18, No. 2, 2018, pp. 437-445
Bioline Code: hs18054
Full paper language: English
Document type: Study
Document available free of charge
African Health Sciences, Vol. 18, No. 2, 2018, pp. 437-445
© Copyright 2018 - Meka et al.
Composition of uroliths in a tertiary hospital in South East Nigeria|
Meka, Ijeoma A; Ugonabo, Martin C; Ebede, Samuel O & Agbo, Ezra O
Background: Urolithiasis affects primarily the urinary tract and complications as debilitating as renal failure may develop. Determining the chemical composition of uroliths can aid management and prevention of recurrence in patients.
Objective: To determine the chemical composition and anatomical distribution of uroliths in Nigeria.
Methods: This descriptive cross-sectional study was conducted between March 2014 and February 2016, in a tertiary hospital
in Nigeria. We reviewed the outcomes of uroliths of adult patients sent to our laboratory for chemical analyses. Samples were
analyzed using simple qualitative tests.
Results: 52 adult patients were included with a mean age (SD) of 46.6 (12.6) years. Males (76.9%) were more affected than
females (23.1%). For both sexes, highest occurrence of stones was in bladder (85.7%). Calcium-containing stones had the highest occurrence (85.2%) and predominated in the renal, ureter and urethra, followed by struvite stones (59.5%). In the bladder,
struvite stones were predominant (85.8%), with calcium-containing stones accounting for 71.4%.
Conclusion: This study showed that struvite and calcium phosphate-containing stones constitute majority of uroliths in our setting with low occurrence of calcium oxalate stones. This indicates that urinary tract infection most likely plays a substantial role
in the formation of uroliths in Nigerians. Modern methods of stone analysis is advocated to further define management options.
Uroliths; calcium oxalate; chemical composition; struvite; stone; calculi