African Health Sciences
Makerere University Medical School
Vol. 18, No. 3, 2018, pp. 837-841
Bioline Code: hs18102
Full paper language: English
Document type: Case Report
Document available free of charge
African Health Sciences, Vol. 18, No. 3, 2018, pp. 837-841
© Copyright 2018 - Sehgal et al.
Nodding syndrome- an Indian case|
Sehgal, Rachna; Agarwal, Neha & Gera, Rani
Background: Although nodding syndrome is a catastrophic epileptic encephalopathy, it is reported only from Africa so far. We
describe the first case from the Indian sub-continent.
Methods: A ten-year-old child who had an episode of Guillain Barre syndrome with incomplete recovery developed emaciation
secondary to bulbar palsy and depression. Subsequently, nine months later she developed head nodding, spastic quadriparesis,
choreo-athetoid movement disorder, global aphasia and depression. She improved with sodium valproate, nutritional rehabilitation and anti-spasticity and anti-depressant medications.
Results: First case of nodding syndrome is described from India where possible etiology is malnutrition. She had anemia, her
electroencephalography revealed parieto-occipital inter-ictal epileptiform discharges and Magnetic Resonance Imaging showed
diffuse cerebral atrophy.
Conclusion: Nodding syndrome is an epileptic encephalopathy of nutritional origin beyond geographical barriers but amenable
to anti-convulsants and nutritional rehabilitation.
Nodding syndrome; India.