Type 2 diabetes mellitus is associated with chronic low grade inflammation. One of the novel inflammatory markers is hemogram derived neutrophil to lymphocyte ratio (NLR).
We aimed to compare NLR levels of diabetic subjects and healthy controls and to observe possible correlation between NLR and HbA1c.
Medical data of type 2 diabetic subjects admitted to out-patient clinics of our institution between April to July in
2017 were obtained from database and retrospectively analyzed. Control group was chosen from healthy subjects who visited our
institution for a routine check-up. Anthropometric measures, laboratory data, including, HbA1c, NLR were recorded.
Median NLR of the type 2 DM group 2.44 (1.9) was significantly elevated when compared to healthy controls (1.5
(0.9), (p<0.001). In addition, a Pearson’s correlation test revealed that NLR was strongly correlated with age (r=0.26, p=0.008),
fasting plasma glucose (r=0.38, p<0.001), and HbA1c (r=0.49, p<0.001).
Elevated NLR in otherwise healthy subjects may be indicative of underlying impaired glucose metabolism and
moreover, NLR should be used as a marker of diabetic control level in addition to HbA1c in type 2 diabetic subjects.
Cite as: Duman TT, Aktas G, Atak BM, Kocak MZ, Erkus E, H S. Neutrophil to lymphocyte ratio as an indicative of diabetic control level
in type 2 diabetes mellitus. Afri Health Sci. 2019;19(1). 1602-1606. https://dx.doi.org/10.4314/ahs.v19i1.35