A retrospective study was conducted in the Bone Marrow Transplant Center of Tunisia during a period of 10 years
(from 2002 to 2011) in order to report the prevalence of infectious multi-drug resistant bacteria.
Bacterial identification was carried on the basis of biochemical characteristics and API identification systems. Antibiotic susceptibility was tested by disc diffusion method on Muller-Hinton agar.
During the study period, 34.5% of 142 Klebsiella pneumoniae
strains and 11.46% of 218 Escherichia coli
strains were extended-spectrum beta-lactamase (ESBL) producers. Also, 32.8% of 210 strains of Pseudomonas aeruginosa
were imipenem and/or
ceftazidime resistant and 20.75% of 106 strains of Staphylococcus aureus
were methicillin resistant. A rising trend was observed for
the prevalence of the selected multidrug resistant bacteria.
These findings may have important clinical implications in prophylaxis and selection of antibiotic treatment. Continuous surveillance is needed, especially for onco-hematological patients.
Cite as: Mechergui A, Achour W, Mathlouthi S, Hassen AB. Prevalence of infectious multi-drug resistant bacteria isolated from immunocompromised patients in Tunisia. Afri Health Sci.2019;19(2): 2021-2025. https://dx.doi.org/10.4314/ahs.v19i2.25