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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 19, No. 4, 2019, pp. 3208-3216
Bioline Code: hs19190
Full paper language: English
Document type: Study
Document available free of charge

African Health Sciences, Vol. 19, No. 4, 2019, pp. 3208-3216

 en Seroprevalence, risk factors and comorbidities associated with Helicobacter pylori check for this species in other resources infection amongst children receiving care at Kilimanjaro Christian Medical Center
Msekandiana, Amos; Msuya, Levina; Philemon, Rune; M'mbaga, Blandina & Kinabo, Grace


Background: Helicobacter pylori frequently causes gastritis and peptic ulcers, and affected children are at risk of developing gastric carcinoma later in adulthood.
Methods: This was a Hospital based cross sectional study. A total of 200 children aged 6 months to 14 years were enrolled. Study subjects were tested for H. pylori using a standard serology rapid test measuring immunoglobulin G for H. pylori. For risk factors, Chi-square tests were used to test for association and then, odds ratios and their corresponding 95% confidence intervals and p-values were computed using logistic regression.
Results: The overall seroprevalence of H. pylori was 11.5%. The following factors were associated with H. pylori infection: Age group above 10 years, keeping a dog and household size. The independent predictors of H. pylori were: Fathers’ occupation, keeping a dog, indoor tap water, age group, household size and diabetes mellitus type 1..
Conclusion: The seroprevalence of H. pylori antibodies was lower compared to most developing countries. Keeping a dog, household size, indoor tap water, fathers’ occupation and diabetes mellitus type 1 were found to be independent predictors of presence of H. pylori antibodies.

Helicobacter Pylori.

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