African Health Sciences
Makerere University Medical School
Vol. 19, No. 4, 2019, pp. 3249-3252
Bioline Code: hs19195
Full paper language: English
Document type: Case Report
Document available free of charge
African Health Sciences, Vol. 19, No. 4, 2019, pp. 3249-3252
© Copyright 2019 - Ezenwosu et al.
Generalized lymphadenopathy: an unusual presentation of burkitt lymphoma in a Nigerian child: a case report|
Ezenwosu, Osita U; Chukwu, Barth F; Okafor, Okechukwu C; Ikefuna, Anthony N & Emodi, Ifeoma J
Intoduction: Burkitt Lymphoma is the fastest growing tumor in human and the commonest of the childhood malignancies.
Generalized lymphadenopathy is a common feature of immunodeficiency associated Burkitt lymphoma but an uncommon presentation
of the endemic type in Human Immunodeficiency Virus (HIV) negative children.
Case presentation: The authors report a 6 year old HIV negative boy who presented with generalized lymphadenopathy, cough,
weight loss, fever and drenching night sweat and had received native medication as well as treatment in private hospitals. His examination
revealed hepatosplenomegaly, bull neck with generalized significant massive lymphadenopathy. Diagnosis was missed
initially until a lymphnode biopsy for histology confirmed Burkitt lymphoma. He was managed on combination chemotherapy
with complete resolution and now on follow up.
Conclusion: To the best of our knowledge, this is the first documented report of its kind of endemic Burkitt lymphoma
involving lymphnodes generally as the primary site. High index of suspicion and early biopsy are the key in this uncommon
Burkitt lymphoma; generalized lymphadenopathy; Nigerian child.