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African Health Sciences
Makerere University Medical School
ISSN: 1680-6905
EISSN: 1680-6905
Vol. 20, No. 2, 2020, pp. 597-604
Bioline Code: hs20023
Full paper language: English
Document type: Study
Document available free of charge

African Health Sciences, Vol. 20, No. 2, 2020, pp. 597-604

 en Salivary flow, amylase, and total protein in hospitalized patients with HIV infection / AIDS complications
Carina de Oliveira, Núbia; Caroline de Oliveira, Thayse; Klamas, Vanessa Cavassin; Ventura, Mateus Anhaia; Kamei, Adryano Arana; Naka, Jhonatan Yukio; Brancher, João Armando & Soares de Lima, Antonio Adilson


Background: Saliva is a complex secretion produced daily by the salivary glands. Saliva consists mainly of water, enzymes, ions and amino acids and performs several important functions in oral health.
Objective: The aim of this study was to investigate the flow rate and concentrations of amylase and total proteins in the saliva of hospitalized patients due to AIDS complications.
Methods: Ninety-three men and women (20-64 years of age) were divided into two groups (46 HIV-infected patients and 47 controls) and had salivary flow rate and levels of amylase enzyme and total proteins evaluated.
Results: The mean salivary flow rate was lower in individuals with HIV when compared to controls (P < 0.05). No significant difference between amylase enzyme levels and total proteins were observed in the saliva of patients with HIV infection when compared to controls.
Conclusion: Individuals with HIV / AIDS infection (in hospital treatment) suffer no interference in levels of amylase and total salivary proteins, but they have significantly reduced salivary flow.

Saliva; Salivation; Alpha-Amylases; Salivary Proteins and Peptides; Xerostomia.

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