African Health Sciences
Makerere University Medical School
Vol. 20, No. 2, 2020, pp. 625-632
Bioline Code: hs20026
Full paper language: English
Document type: Study
Document available free of charge
African Health Sciences, Vol. 20, No. 2, 2020, pp. 625-632
© Copyright 2020 - Mukasa J et al.
Adherence to the MDR-TB intensive phase treatment protocol amongst individuals followed up at central and peripheral health care facilities in Uganda - a descriptive study|
Mukasa, Joseph; Kayongo, Edward; Kawooya, Ismael; Lukoye, Deus; Etwom, Alfred; Mugabe, Frank; Tweya, Hannock; Izizinga, Rose & Mijumbi-Deve, Rhona
Background: Following initiation of MDR-TB treatment, patients have a choice to receive follow up DOT supervision at
either the central initiating facility or at a peripheral facility.
Objectives: We describe the adherence patterns of MDR-TB patients undergoing DOT supervision at the two health
facility categories during intensive phase of treatment.
Methods: We used a retrospective cohort of patients initiated on MDR TB treatment at Mulago National Referral Hospital
between 2014 and 2016. We extracted data from the National Tuberculosis and Leprosy Program records and analysed these
using STATA V14.
Results: Majority (84.01%) of the patients received their DOT supervision from the peripheral facilities. Males made up 62.1% of patients, and 91.2% had had their household contacts screened for MDR-TB. 26.5% of the patients on peripheral DOT supervision had good adherence to treatment protocol compared to 0% among patients on central initiating health facility DOT supervision. Among the patients with good adherence, 24.1% had contacts screened for MDR-TB as compared to 3.6% with poor adherence.
Conclusion: More patients preferred MDR-TB DOT supervision at peripheral facilities, which had better adherence to the treatment protocol compared to the central initiating facility. Younger people and those with household contacts screened had better adherence to the treatment protocol, highlighting areas for targeted interventional programs for MDR-TB in resource limited settings.
MDR-TB; adherence; central initiating; peripheral health facility; DOTS; SORT IT.