An evaluation of six-year Stenotrophomonas maltophilia infections in a university hospital|
Ince, Nevin; Yekenkurul, Dilek; Danış, Ayşe; Çalışkan, Emel & Akkaş, İdris
Background: Stenotrophomonas maltophilia is a Gram-negative bacillus and opportunistic emergent pathogen causing hospital-acquired infections (HAIs). Due to risk factors such as prolonged intensive care unit stay and invasive procedures, it has
become one of the leading causes of HAIs.
Objective: The aim of this study was to evaluate the epidemiology of S.maltophilia infections over a six-year period at Düzce
University Hospital, Turkey.
Methods: The incidence, clinical characteristics, antimicrobial susceptibility and outcomes of nosocomial S. maltophilia infections
during this period were retrospectively analyzed.
Results: During the study period, 67 samples obtained from 61 patients were identified. Pneumonias (82%) were the most
common HAIs, followed by bloodstream infections (10.5%), urinary tract infections (3%), skin and soft tissue infections
(3%) and surgical site infection (1.5%). Admission to intensive care, hospitalization exceeding 30 days, and previous use of
broad-spectrum antibiotics constituted risk factors. Resistance to cotrimoxazole (6%) was lower than that to levofloxacin
Conclusion: The most important risk factors for S.maltophilia infection in patients are previous exposure to antibiotics, prolonged
hospitalization and invasive procedures such as mechanic ventilation. Discharging patients as early as possible with
the rational use of antibiotics may be effective in reducing S. maltophilia infections and resistance rates.
Stenotrophomonas maltophilia; hospital-acquired infections; epidemiology; risk factors.