Epidemiology and survival analyses of 333 adult glioma patients from Eastern Algeria (2008-2016)|
Touati, Sabrina; Djekkoun, Rachid; Okki, Mohamed El-Hadef El- & Satta, Dalila
Background: Gliomas are a relatively rare group of tumors with a poor prognosis. We aimed to describe and analyze the
clinical characteristics and survival of patients with glioma tumors of Eastern Algeria.
Methods: A retrospective study was conducted at the University Hospital of Constantine. Medical records of patients
enrolled between January 2008 and October 2016 were consulted. Demographic characteristics, clinical data, treatment
strategy and dates of last follow-up or death were collected. Chi-square test was used for checking associations, Kaplan-Meier methodology for estimating the survival, and the cox model for identifying prognosis factors.
Results: A total of 333 patients composed our cohort. The mean age was 48.07 years, and men were 1.87 times more
frequent than women. High grade tumors were mainly observed among adults and old adults and in supra-tentorial locations.
More than half of the patients had a large resection and a curative protocol of oncological treatment (50.7% and 57%, respectively).
The mean overall survival was 45.4 months, the median was 21.7 months, and survival rates at 1-, 2-, and 5-years
were: 62.8%, 48.5% and 32.9% respectively. Age, histology, grade of malignancy and oncological treatment were the major
Conclusion: Our sample was relatively young with a higher survival compared to others.
Glioma; epidemiology; Algeria.