African Health Sciences
Makerere University Medical School
Vol. 20, No. 4, 2020, pp. 1537-1545
Bioline Code: hs20110
Full paper language: English
Document type: Research Article
Document available free of charge
African Health Sciences, Vol. 20, No. 4, 2020, pp. 1537-1545
© Copyright 2020 - Nyagaka B et al.
Characteristics and treatment outcomes of HIV infected elderly patients enrolled in Kisii Teaching and Referral Hospital, Kenya|
Nyagaka, Benuel; Musyoki, Stanslaus Kiilu; Karani, Lucy & Nyamache, Anthony Kebira
Background: A better understanding of the baseline characteristics of elderly people living with HIV/AIDS (PLWHA) is
relevant because the world’s HIV population is ageing.
Objectives: This study aimed to evaluate the baseline characteristics of PLWHA aged ≥ 50years at recruitment to HIV/AIDS clinic compared against the viral load (VL) and CD4 count among patients attending Kisii Teaching and Referral
Hospital (KTRH), Kenya.
Methods: We retrospectively evaluated temporal inclinations of CD4 levels, viral load change and baseline demographic
characteristics in the electronic records at the hospital using a mixed error-component model for 1329 PLWHA attending
clinic between January 2008 and December 2019.
Results: Findings showed a significant difference in the comparison between baseline VL and WHO AIDS staging (p=0.026).
Overall VL levels decreased over the period significantly by WHO AIDS staging (p<0.0001). Significant difference was observed
by gender (p<0.0001), across age groups (p<0.0001) and baseline CD4 counts (p=0.003). There were significant
differences in WHO staging by CD4 count >200cell/mm3 (p=0.048) and residence (p=0.001).
Conclusion: Age, WHO AIDS staging, gender and residence are relevant parameters associated with viral load decline and
CD4 count in elderly PLWHA. A noticeable VL suppression was attained confirming possible attainment of VL suppression
among PLWHA under clinical care.
HIV infected elderly patients; Kisii Teaching and Referral Hospital; Kenya.