The optimal management of community acquired pneumonia (CAP) depends on the clinical and microbiological
profile in the locality.
To determine the clinical and microbiological profile of patients admitted with CAP in Ilorin, Nigeria.
One hundred and two consenting consecutively selected patients with clinical and radiologic confirmation of
CAP were recruited in 12 months. The socio-demographic, physical examination and laboratory/radiologic parameters were
documented in a questionnaire. Microbiological evaluation of their sputum was done and blood samples were taken for
complete blood count, culture, serum urea and serological evaluation for atypical bacteria and some viral pathogens.
CAP constituted 5.9% of the total medical admissions during the one-year study period. The mean age of the patients
was 49 ± 22 years with the largest frequency in those aged 65 years and above. The commonest symptoms were shortness
of breath (96.1%) and cough (94.1%), with a median duration of 3 days from symptom onset to admission. Systemic
hypertension was the commonest comorbid illness (25/102; 24.5%). Klebsiella pneumoniae
was the predominant pathogen isolated
(20/102; 28.1%). The susceptible antibiotics were Imipenem, Ceftazidime and Ceftriaxone. Intra-hospital mortality was
17.6%. CURB – 65 score of ≥ 2 and the presence of complications of CAP were the independent predictors of mortality.
CAP constitutes a significant disease burden in Ilorin, Nigeria. Typical bacteria accounted for over half of the
pathogens isolated from the patients with gram negative agents predominating. This highlights a possible shift in the microbiological
profile which could guide empirical treatment.