African Health Sciences
Makerere University Medical School
Vol. 20, No. 4, 2020, pp. 1927-1932
Bioline Code: hs20157
Full paper language: English
Document type: Study
Document available free of charge
African Health Sciences, Vol. 20, No. 4, 2020, pp. 1927-1932
© Copyright 2020 - Mishra S et al.
Transverse cerebellar diameter: a reliable predictor of gestational age|
Mishra, Sanjay; Ghatak, Surajit; Singh, Pratibha; Agrawal, Dushyant & Garg, Pawan
Objectives: To determine accuracy of transverse cerebellar diameter (TCD) measurement in the prediction of gestational
age (GA) in normal fetuses; to develop reference chart for TCD according to GA in Indian population.
Design: A retrospective cross-sectional study.
Method: Ultrasonographic measurements in 300 singleton pregnant women included biparietal diameter (cm), head circumference
(cm), abdominal circumference (cm), femur length (cm) and transverse cerebellar diameter (cm). Reference chart
with mean TCD for corresponding gestational age (GA) in weeks was developed.
Results: Statistically significant relationship found between TCD and gestational age (R2=0.92, p=0.0006). Regression formulae
based on TCD with other parameter can be used to predict gestational age of foetus. When TCD is compared with
findings in other studies in different ethnic population, it is found that there is significant difference exists.
Conclusion: In normally developing fetuses the TCD has linear correlation with advancing gestational age. A separate reference
chart is required for every different population because ethnicity, nutrition and environmental factors can have impact
on normal TCD values. This will help to avoid misinterpretation of data to determine gestational age.
Transverse cerebellar diameter; ultrasonography; gestational age.