African Health Sciences
Makerere University Medical School
Vol. 21, No. 1, 2021, pp. 54-59
Bioline Code: hs21019
Full paper language: English
Document type: Research Article
Document available free of charge
African Health Sciences, Vol. 21, No. 1, 2021, pp. 54-59
© Copyright 2021 - Amin SM et al.
Histopathologic spectrum of childhood tumours in a Tertiary Hospital: a ten-year review|
Amin, Said M; Nwatah, Vincent E; Ameh, Emmanuel A; Oyesegun, Abdurasaq R & Oyesakin, Adewumi B
Background: There has been a growing public health burden of childhood tumours in low and middle income countries
(LMICs) as the trend in epidemiological transition continues to vary.
Objective: The objective of this report is to determine the spectrum of childhood tumours at a tertiary hospital in Nigeria.
Methods: A retrospective review of the histopathology register over the period January 2006 to December 2015.
Results: The total paediatric tumour cases was 248, including 143 (57.7%) females and 105 (42.3%) males, aged 0 – 12 years
(mean 6.1years ± 3.97 SD). The age group 2 - 5 year cohort had the highest prevalence of tumour. The predominant tumour
based on tissue of origin was epithelial neoplasms 88 (35.5%), vascular neoplasms 56 (22.6%), neural neoplasm 42 (16.9%),
mesenchymal neoplasm 37 (14.9%), germ cell neoplasm 13 (5.2%) and haematopoietic neoplasms 12 (4.8%). Majority of the
tumours were benign, 148 (59.7%) and malignant 100 (40.3%). The most predominant benign tumour was haemangioma 33
(13.3%) and predominant malignant tumour was lymphoma 22 (8.9%).
Conclusion: Benign tumours remain the commonest neoplasm of children in this hospital-based data. Development and
implementation of a tumour registry would provide a more comprehensive information.
Childhood tumours; spectrum; haemangioma; lymphoma.