African Health Sciences
Makerere University Medical School
Vol. 21, No. 1, 2021, pp. 64-71
Bioline Code: hs21022
Full paper language: English
Document type: Research Article
Document available free of charge
African Health Sciences, Vol. 21, No. 1, 2021, pp. 64-71
© Copyright 2021 - Dikobe W et al.
The utility of a modified WHO TB screening tool among children at a Botswana child welfare clinic|
Dikobe, Wame; Molefi, Mooketsi; Nkomo, Bornapate; Kgwaadira, Botshelo; Gasenelwe, Boingotlo; Seloilwe, Esther; Mashalla, Yohanna & Mills, Tonya-Ascortt
Background: In high TB/HIV settings, the increased risk for TB amongst children exposed to HIV has been established
through biomedical tests. Screening HIV exposed children for TB can improve early childhood TB detection and treatment.
Objective: This study assessed the utility of a modified World Health Organization (WHO) tool by including HIV variables,
to determine TB exposure amongst HIV exposed children presenting to a “Well Child” Clinic (CWC).
Methods: Clinical data were obtained from medical records and/or from the caregivers of children presenting to CWC.
Data was analyzed to explore factors associated with positive screening for TB, including being exposed to HIV and current
Results: Five percent (55/1100) screened reported a close TB contact and 21% (n=231) had positive TB symptom screen.
History of close TB contact was a risk factor for positive screening for TB symptoms (OR 1.89 CI 1.05-3.4) while being
HIV negative was protective (OR 0.3, Cl 0.19-0.62). HIV exposure was associated with increased risk of TB exposure (OR
2.9 CI 1.61-5.19).
Conclusion: Integrating HIV variables in the existing WHO screening tool for childhood TB can be useful in early detection
and treatment of TB in HIV exposed children in resource limited settings.
Childhood TB screening; HIV Exposure screening; TB/HIV integration.