Mixed ligand-metal complexes of Paracetamol and Ascorbic acid were synthesized using FeCl
2.4H
2O,
CuCl
2.2H
2O, NiCl
2.6H
2O, CoCl
2.6H
2O and ZnSO
4 salts based on two concentrations (3mmol and 5mmol). The
complexes were characterized using some physical techniques such as melting point, solubility, conductivity
measurement and spectroscopic analyses such as UV-Visible spectroscopy, Atomic absorption spectroscopy, and
Infrared spectroscopy. Based on the physical and spectroscopic results, the coordination of the metal was through the
phenolic oxygen and carbonyl oxygen in paracetamol while it was through the carbonyl oxygen and C-2 hydroxyl group
in ascorbic acid. The complexes were also screened for their antimicrobial activities against some isolates of
Enterococcus faecalis
,
Staphylococcus aureus
,
Clostridium difficile
,
Klebsiella sp.
,
Helicobacter pylori
.