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Journal of Applied Sciences and Environmental Management
World Bank assisted National Agricultural Research Project (NARP) - University of Port Harcourt
ISSN: 1119-8362
Vol. 21, No. 6, 2017, pp. 1223-1225
Bioline Code: ja17152
Full paper language: English
Document type: Research Article
Document available free of charge

Journal of Applied Sciences and Environmental Management, Vol. 21, No. 6, 2017, pp. 1223-1225

 en Anti-inflammatory Activity of Methanoilc and Ethanolic Extracts of Citrus sinensis check for this species in other resources peel (L) Osbeck on Carrageenan induced Paw Oedema in Wistar rats
OSARUMWENSE, .P.O

Abstract

Aqueous ethanoic and methanolic extracts of Citrus Sinensis Peel were investigated for antiinflammatory activity in carrageenan induced paw oedema in wistar rats, and compared to a positive control drug, Indomethacin. These extracts were given(IP) in a concentration of 20, and 70mg/kg with extract with a concentration whichshowed maximum(95%) inhibition on carrageenan induced rat paw oedema. The effect was significantly higher than that of the standard drug indomethacin (93%).Methanol extract with a concentration of 40mg/kg produced 95% inhibition, which was also high as compared to the standard drug. Ethanolic extracts with doses of 20mg/kg and 40mg/kg produce less percentage of inhibition as compared to the standard drug Indomethacin.

Keywords
Citrus Sinensis; Anti-inflammation; Carrageenan; Peels; anti-inflammatory; ethanolic extract.

 
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