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Journal of Applied Sciences and Environmental Management
World Bank assisted National Agricultural Research Project (NARP) - University of Port Harcourt
ISSN: 1119-8362
Vol. 22, No. 2, 2018, pp. 237-245
Bioline Code: ja18043
Full paper language: English
Document type: Research Article
Document available free of charge

Journal of Applied Sciences and Environmental Management, Vol. 22, No. 2, 2018, pp. 237-245

 en Antibacterial activity of Methanol and Chloroform extracts of Spilanthes oleracea check for this species in other resources plant on isolated pathogenic oral bacteria
ONORIODE, O & OSHOMOH, EO

Abstract

Dental caries is an infectious and transmissible disease caused by the colonization of tooth surfaces by normal oral flora, including Streptococcus check for this species in other resources and Lactobacillus check for this species in other resources species. Routine use of broad spectrum antibiotics in the treatment of dental caries including postoperative prophylactic use, has led to widespread bacteria resistance to antibiotics, a situation that currently pose a global threat to public health. Spilanthes oleracea, popularly known as the toothache plant, is widely used for the treatment of toothache, sore throat and gum infections. Although a large number of antimicrobial effects have been reported against gram positive and gram negative species, only a small number of S.oleracea have been studied for biochemical activity. The crude extracts of S. oleracea showed very potent antimicrobial activity against a population of isolated pathogenic oral organisms. 20mg/ml each of crude methanol and dichloromethane extracts of S. oleracea leaves produced average zones of inhibition ranging between 21mm and 29mm (in diameter) against isolated Streptococcus mutans check for this species in other resources and Lactobacillus species, while 20mg/ml of crude methanol extracts of S. oleracea flowers produced average zones of inhibition of 28mm and 25mm (in diameter) against S. mutans and Lactobacillus species respectively. Findings indicate that polar and non-polar extracts of S. oleracea could potentially function as an alternative to synthetic antibiotics in the treatment of oral infections and dental caries.

Keywords
Cariogenic; dental caries; antimicrobial; pharmacological activities

 
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