Several species of the genus
Tapinanthus have folkloric use by the Hausa and Fulani tribes of the
Northern Nigeria as a remedy for numerous human and animal ailments including stomach ache, diarrhea, dysentery,
wounds and swellings. The preliminary phytochemical screening of the stem bark of
Tapinanthus globiferus, was
carried out using standard method. The result of the phytochemical screening of crude ethylacetate, n-hexane extract
revealed the presence of carbohydrate, flavonoids steroids and terpenes. The antimicrobial screening against
Candida krusei
, methicillin resistant
Staphylococcus aureus
,
Campylobacter jejuni
,
Streptococcus pyogenes
,
vancomycin resistant enterococci,
Helicobacter pylori
,
Escherichia coli
,
Shigella dysenteriae
,
Staphylococcus aureus and
Candida tropicalis
was done using agar well diffusion method. The zone of inhibition of growth of microorganisms ranged from
22-28mm for the ethylacetate extract, and 18-21mm for the n-hexane extract and the minimum inhibitory concentration
of the extracts was found to be between 0.63mg/ml and 20mg/ml while the minimum bactericidal/fungicidal
concentration were found to be between 0.63mg/ml and 20mg/ml. This research has establish a baseline information on
the efficacy of the crude extracts of
Tapinanthus globiferus.
