This study was conducted to estimate the prevalence of intestinal parasitic infestations among school children in Kaski District of Western Nepal. A total of 2091 stool samples were collected from school children selected from 11 rural and eight urban schools. The stool samples were examined for evidence of parasitic infections by direct microscopic examination. Prevalence of intestinal parasites was 21.3%. There was a significant difference in prevalence between urban (18.7%) and rural (24.1%) school samples. Giardia lamblia
(13.2%), Ascaris lumbricoides
(2.1%) and Entamoeba histolytica
(1.7%) were the commonest parasites isolated. The results indicate that intestinal parasitic infestation among school children in the study area is mainly water-borne. The burden of parasitic infestations among the school children, coupled with the poor sanitary conditions in the schools, should be regarded as an issue of public health priority. This strongly supports the need for school health programmes that will involve periodic deworming, health education and improvement of school sanitation.