Drug Review - Atorvastatin: In The Management Of Hyperlipidaemia

The proved association between hypercholesterolaemia with development of atherosclerosis and coronary heart disease warrants reduction in high levels of serum cholesterol (TC) and low-density-lipoprotein cholesterol (LDL-C). Since the discovery, HMG-CoA reductase inhibitors are considered as one of the most effective classes of drugs for reducing LDL-C and TC.¹ Recently in India, atorvastatin calcium has been added to the list of available HMG-CoA reductase inhibitors (lovastatin and simvastatin).