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Journal of Postgraduate Medicine
Medknow Publications and Staff Society of Seth GS Medical College and KEM Hospital, Mumbai, India
ISSN: 0022-3859
EISSN: 0022-3859
Vol. 48, No. 4, 2002, pp. 327 		Bioline Code: jp02108
Full paper language: English
Document type: Research Article
Document available free of charge

Journal of Postgraduate Medicine, Vol. 48, No. 4, 2002, pp. 327

 en Letter to the Editor - Methylene Blue as Treatment for Contrast Medium-induced Anaphylaxis
Evora PR, Oliveira Neto AM, Duarte NM, Vicente WVA

Abstract

Nitric oxide seems to play an important pathophysiological role in modulating the systemic changes associated with anaphylaxis.1 Considering nitric oxide to be the final mediator of vasoplegia, we have used methylene blue to treat anaphylactic shock secondary to radio-contrast material and penicillin2 in three patients, with a good immediate response. We have also used the drug to treat vasoplegia in cardiac surgery.3,4,5,6

 
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