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Journal of Postgraduate Medicine
Medknow Publications and Staff Society of Seth GS Medical College and KEM Hospital, Mumbai, India
ISSN: 0022-3859
EISSN: 0022-3859
Vol. 56, No. 1, 2010, pp. 42-43
Bioline Code: jp10016
Full paper language: English
Document type: Report
Document available free of charge

Journal of Postgraduate Medicine, Vol. 56, No. 1, 2010, pp. 42-43

 en Atropine-induced rhabdomyolysis: An uncommon and potentially fatal adverse drug reaction
Akhtar, S.; Rai, M. K.; Dutta, T. K.; Subrahmanyam, D.K.S. & Adithan, C.

Abstract

A 25 year old woman received daily injection of 0.6 mg atropine for seven days by the intra-venous route. In addition to fever, incomprehensible speech and alteration of sensorium she developed albuminuria, hemoglobinuria and myoglobinuria. A diagnosis of atropine-induced rhabdomyolysis was made on the basis of clinical presentations and investigations. Although, datura poisoning and intoxication with wild mushrooms are known to result in rhabdomyolysis, this can be considered to be the first case of atropine-induced rhabdomyolysis and myoglobinuria.

Keywords
Adverse drug reaction, atropine, rhabdomyolysis

 
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