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Journal of Postgraduate Medicine
Medknow Publications and Staff Society of Seth GS Medical College and KEM Hospital, Mumbai, India
ISSN: 0022-3859 EISSN: 0022-3859
Vol. 56, No. 3, 2010, pp. 229-231
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Bioline Code: jp10069
Full paper language: English
Document type: Report
Document available free of charge
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Journal of Postgraduate Medicine, Vol. 56, No. 3, 2010, pp. 229-231
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Esomeprazole-induced photoallergic dermatitis
Shukla, A.; Mahapatra, A.; Gogtay, N. & Khopkar, U.
Abstract
There are no published case reports of esomeprazole-induced photoallergic dermatitis. We report here a 58-year-old lady with prior history of propylthiouracil and carbimazole-induced photoallergy, who presented with heartburn and dysphagia. She was diagnosed to have erosive esophagitis and was treated with esomeprazole, following which she developed photoallergic dermatitis. It improved on cessation of the drug and did not recur on subsequent treatment with ranitidine. Naranjo score for this adverse drug event was 8, thereby making it a probable adverse drug reaction. This reaction may be due to sulphur moiety, which is common to all these drugs. Physicians must be aware of this possible side-effect, especially in patients with prior history of photoallergy to other drugs.
Keywords
Adverse drug reaction, photoallergy, proton pump inhibitors
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