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Journal of Postgraduate Medicine
Medknow Publications and Staff Society of Seth GS Medical College and KEM Hospital, Mumbai, India
ISSN: 0022-3859 EISSN: 0022-3859
Vol. 56, No. 4, 2010, pp. 307-316
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Bioline Code: jp10091
Full paper language: English
Document type: Review Article
Document available free of charge
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Journal of Postgraduate Medicine, Vol. 56, No. 4, 2010, pp. 307-316
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Multiple ring-enhancing lesions of the brain
Garg, R.K. & Sinha, M.K.
Abstract
Multiple ring-enhancing lesions of the brain are one of the most commonly encountered abnormalities on neuroimaging. These can be caused by a variety of infectious, neoplastic, inflammatory or vascular diseases. Distinguishing non-neoplastic causes from neoplastic lesions is extremely important because a misdiagnosis can lead to unwarranted neurosurgery and exposure to toxic chemotherapy or potentially harmful brain irradiation. Diligent clinical evaluation and a battery of tests are required for making a definitive diagnosis. Newer advanced diagnostic techniques, such as diffusion-weighted magnetic resonance imaging (MRI), perfusion-weighted MRI, magnetic resonance spectroscopy, single-photon emission tomography and positron emission tomography may help in establishing the etiology. However, early brain biopsy is often needed because several of these diseases are potentially life-threatening.
Keywords
Brain tumor, metastasis, neurocysticercosis, neuroimaging, tuberculoma
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