A wide range of fungi have been associated with Allergic Fungal Sinusitis (AFS) or Eosinophilic fungal rhinosinusitis ( EFRS) as it is known in some institutions. To our knowledge, this is the first reported case of aggressive, invasive AFS due to
Acremonium
species occurring in an immunocompetent patient and leading to unilateral visual loss. Literature on AFS is reviewed.