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East and Central African Journal of Surgery
Association of Surgeons of East Africa and College of Surgeons of East Central and Southern Africa
ISSN: 1024-297X
EISSN: 2073-9990
Vol. 15, No. 2, 2010, pp. 144-149
Bioline Code: js10051
Full paper language: English
Document type: Research Article
Document available free of charge

East and Central African Journal of Surgery, Vol. 15, No. 2, 2010, pp. 144-149

 en Extra-adrenal Pheochromocytoma: Experience in Mulago Hospital
Alema, O.N. & Fualal, J.O.


Exta-adrenal pheochromocytomas are rare tumors that arise from extra-adrenal chromaffin cells of the sympathetic ganglia. Experience with two cases is reported here and a review of literature was conducted. Like pheochromocytomas, extra-adrenal pheochromocytomas present with episodic hypertension, tachycardia, headache, and diaphoresis, and can be either benign or malignant. Diagnosis is made by serum and urine analysis for catecholamines and metanephrines, and confirmed with imaging studies including computed tomography scanning, magnetic resonance imaging, or 123-I metaiodobenzylguanidine imaging. Ultrasound scanning in the developing world is beneficial. Genetic testing should be offered were available, particularly patients who are young, have multiple tumors, or have a family history of malignancy. Management of extra-adrenal pheochromocytoma is enblock en-mass surgical resection. Chemotherapy, and radiation therapy may be necessary in malignant disease. Long-term follow-up is essential, as extra-adrenal pheochromocytomas can recur many years after initial diagnosis.

© Copyright 2010 East and Central African Journal of Surgery.

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