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East and Central African Journal of Surgery
Association of Surgeons of East Africa and College of Surgeons of East Central and Southern Africa
ISSN: 1024-297X EISSN: 1024-297X
Vol. 17, No. 1, 2012, pp. 104-111
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Bioline Code: js12019
Full paper language: English
Document type: Research Article
Document available free of charge
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East and Central African Journal of Surgery, Vol. 17, No. 1, 2012, pp. 104-111
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Comparision of Fine Needle Aspiration Cytology and Fine Needle Sampling without Aspiration in Diagnosis of Palpable Breast Lumps in Mulago Hospital.
Alema, O.N.; Gakwaya, A.M & Wamala, D.
Abstract
Background: Open biopsy of the breast used to be the main traditional method of diagnosis of breast lumps. Fine Needle Aspiration Cytology (FNAC) was later introduced which depends on suction and thus yields hemorrhagic material for cytological study.This study was undertaken
to find out if there is a difference in diagnostic accuracy in using Fine Needle Aspiration
Cytology and Fine Needle Sample (FNS) without aspiration in the diagnosis of palpable breast
lumps.
Methods: This was a cross-sectional study of women with palpable breast masses of 2cm and
above in the widest diameter by ultrasound. Patients were subjected to FNS, FNAC and excision
biopsy of the lump or mastectomy where appropriate. Cytodiagnosis of all the cases was
compared to the histodiagnoses of the biopsies to establish the sensitivity, specificity and
diagnostic accuracy.
Results: Some 85 patients had FNS, FNAC and excision biopsy/ mastectomy done. The findings
demonstrated that both FNS and FNAC have the same sensitivity of 83.3%, specificity of 100%
and diagnostic accuracy of 98.7% in the diagnosis of palpable breast lumps. FNS had good
quality smears in 88.2% of the patients as compared to FNAC smears which was 58.8%of the
patients.FNS smears were adequate in 95.3% of the patients as compared to FNAC smears
which was adequate in 90.6% of the patients.
Conclusion: There was no difference in the diagnostic accuracy of FNS and FNAC in the
diagnosis of palpable breast lumps. These findings may suggest that it is probably the adequacy
of the cells harvested rather than the quality of the cells harvested which determines the
difference in the diagnostic accuracy of the two techniques.
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© Copyright 2012 - East and Central African Journal of Surgery
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