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East and Central African Journal of Surgery
Association of Surgeons of East Africa and College of Surgeons of East Central and Southern Africa
ISSN: 1024-297X EISSN: 1024-297X
Vol. 17, No. 2, 2012, pp. 43-47
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Bioline Code: js12034
Full paper language: English
Document type: Research Article
Document available free of charge
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East and Central African Journal of Surgery, Vol. 17, No. 2, 2012, pp. 43-47
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Masquelet's Technique for Management of Long Bone Defects: From Experiment to Clinical Application
Motsitsi, N.S.
Abstract
Bone defect, of whatever cause, is clinically challenging to treat. Defects of up to 4.0 cm
can be successfully treated with cancellous bone grafting. Large defects require more complex
alternatives like, bone transport, vascularized bone grafting, allografts or fibular pro-tibia
grafting. There are advantages and disadvantages to these techniques and patient's
cooperation is critical for successful outcome. None of these treatment options are reliably
successful. The Masquelet's technique is a viable option in the management of large defects.
It is based on two principal steps: the formation of induction membrane and cancellous
bone grafting. Defects as large as 25 cm can be successfully treated with this technique. The
induction membrane is a viable tissue that plays a role in bone formation or incorporation.
It has been demonstrated experimentally that the membrane contains elements that are
important in bone formation and vascularization of cancellous bone placed inside the
induction membrane. Research in still needed on this membrane in human subjects.
Clinically the Masque let technique has been shown to be successful. The originator of the
technique has the largest series to date plus the longest follow-up. Other clinicians have also
shared their experience using the technique. Clinically more cases need to reported and guidelines
established.
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© Copyright 2012 - East and Central African Journal of Surgery
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