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East and Central African Journal of Surgery
Association of Surgeons of East Africa and College of Surgeons of East Central and Southern Africa
ISSN: 1024-297X
EISSN: 2073-9990
Vol. 17, No. 3, 2012, pp. 3-11
Bioline Code: js12043
Full paper language: English
Document type: Research Article
Document available free of charge

East and Central African Journal of Surgery, Vol. 17, No. 3, 2012, pp. 3-11

 en Aetiology and Impact of Intra-abdominal Sepsis on Surgical Management
Weledji, E.P. & Cnichom, A.M.

Abstract

An overview of intra-abdominal sepsis is necessary at this time with new experimental studies and audits on management outcomes. The understanding of the pathophysiology of the peritoneum in the manifestation of surgical sepsis and the knowledge of the source of pathogenic organisms which reach the peritoneal cavity are crucial to the prevention of intra-abdominal infection. Recent advances in interventional techniques for peritonitis have significantly reduced the morbidity and mortality of physiologically severe complicated abdominal infection. Sepsis is an evolving process and the sequelae reflect the increasing severity of the systemic response to infection. Prevention entails early recognition, prompt resuscitation and early surgical intervention to abort the process. Sepsis represents a major clinical challenge and their management demands a multidisciplinary approach.

 
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