Management of Giant Craniofacial Ossifying Fibroma – Case Series Report.

Although ossifying fibroma (OF) is a slow growing neoplasm, some lesions may behave aggressively reaching massive proportions that may demand special treatment. OF of the head and neck is most commonly described in the mandible and maxilla. A few isolated reports in the literature exhibit the rare existence of this lesion in the nasal bone, orbit, ethmoid sinus, sphenoid sinus, frontal sinus, temporal bone, and intracranial region. Three cases of massive OF of the midface with intracranial extension are reported. The management protocol of these lesions is presented and discussed.